王鹏,博士,副教授,博士生导师。必赢766net手机版生物医学工程教研室。主要从事小分子荧光探针在肿瘤早期诊断中的应用、靶向抗肿瘤药物分子的设计活性研究、基于有机小分子荧光探针的智控载药系统等方面的研究。主持国家自然科学基金、江苏省自然科学基金、中央高校基本科研项目以及校级项目多项。入选江苏省青蓝工程优秀青年骨干教师(2018)、江苏省双创计划“科技副总”(2018)等计划。近5年以第一作者或通讯作者在Chemical Science、Small、BiomaterialsBiosensors and BioelectronicsACS Applied Materials & Interfaces、Sensors and Actuators B: ChemicalAnalytica Chimica ActaEuropean Journal of Medicinal ChemistryMolecular Pharmaceutics、Nanomedicine等学术期刊发表SCI学术论文四十余篇;申请中国发明专利6项,授权4项;参与研发的抗肿瘤1.1类新药于20204月进入II期临床试验。


主要学习及工作经历:
2014.7—至今必赢766net手机版

2018.102019.10 美国哈佛医学院/麻省总医院Martinos Center 访问学者
2011.32014.6 东南大学生物医学工程专业 博士
2005.92008.6 中国药科大学药学院药物化学专业 硕士
2001.92005.6 山东大学药学院药学专业本科


研究兴趣:
小分子荧光探针在肿瘤早期诊断及诊疗中的应用
靶向抗肿瘤药物分子的设计活性研究
基于有机小分子荧光探针的智控载药系统


代表性论文

1. Jing Yang, Biyue Zhu, Wei Yin, Zhihao Han, Chao Zheng, Peng Wang*, Chongzhao Ran*. Differentiating Aß40 and Aß42 in amyloid plaques with a small molecule fluorescence probe. Chemical Science, 2020.

2. Han Wang, Zhaohui Wang, Yuanbiao Tu, Yongkuan Li, Tian Xu, Man Yang, Peng Wang, Yueqing Gu. Homotypic targeting upconversion nano-reactor for cascade cancer starvation and deep-tissue phototherapy. Biomaterials, 235 (2020) 119765

3. Han Wang, Zhaohui Wang, Yongkuan Li, Tian Xu, Qi Zhang, Man Yang, Peng Wang,* Yueqing Gu*.A Novel Theranostic Nanoprobe for In Vivo SingletOxygen Detection and Real-Time Dose–Effect Relationship Monitoring in Photodynamic Therapy, Small, 2019, 1902185.

4. Wang Peng*Wang QianqianHuang JinxinLi NanGu Yueqing *A dual-site fluorescent probe for direct and highly selective detection of cysteine and its application in living cells,Biosensors and Bioelectronics,2017,92583~588.

5. Han Wang, Yongkuan Li, Man Yang, Peng Wang*, and Yueqing Gu*, FRET-Based Upconversion Nanoprobe Sensitized by Nd3+ for theRatiometric Detection of Hydrogen Peroxide in Vivo, ACS Appl. Mater. Interfaces 2019, 11, 7441−7449.

6. Lili Xia, Fang Hu, Jinxin Huang, Nan Li, Yueqing Gu*, Peng Wang*, A fluorescent turn-on probe for nitroreductase imaging in living cellsand tissues under hypoxia conditions, Sensors and Actuators B, 2018, 268: 70–76.

7. Yuxiang Ma, Ying Zhao, Lili Xia, Jinxin Huang, Yueqing Gu, Peng Wang*, A novel one- and two-photon fluorescent probe induced by light for selective imaging of Cys in living cells and tissues, Analytica Chimica Acta, 2018, 1035: 161-167.

8. Huang JinxinLi NanWang QianqianGu Yueqing*Wang Peng*A lysosome-targetable and two-photon fluorescent probe for imaging endogenous β-galactosidase in living ovarian cancer cellsSensors and Actuators B: Chemical2017246833~839.

9. Wang Peng*Huang JinxinWang KeGu Yueqing*New Palbociclib analogues modified at the terminal piperazine ring and their anticancer activitiesEuropean Journal of Medicinal Chemistry2016122546~556.

10. Wang Peng*Cai JinChen JunqingJi Min*Synthesis and anticancer activities of ceritinib analogs modified in the terminal piperidine ringEuropean Journal of Medicinal Chemistry2015931~8.


联系方式:
wangpeng@cpu.edu.cn


王鹏
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