制药工程学(学硕、学博)

  1. Jingxuan Guo, Jia Sun, Donghui Liu, Ji Liu, Lijuan Gui, Man Luo, Dexin Kong, Sainaiwaiergul Wusiman, Chang Yang, Ting Liu,* Zhenwei Yuan*, and Ruixi Li*, Developing a Two-Photon “AND” Logic Probe and Its Application in Alzheimer’s Disease Differentiation, Analytical Chemistry, 2023, 95, 16868−16876.

  2. Jun Yan, Kaizhen Wang, Lijuan Gui, Xian Liu, Yingying Ji, Jingjing Lin, Man Luo, Hong Xu, Jingxuan Lv, Fang Tan,* Liangting Lin,* and Zhenwei Yuan*, Diagnosing Orthotopic Lung Tumor Using a NTR-Activatable Near Infrared Fluorescent Probe by Tracheal Inhalation, Analytical Chemistry, 2023, 95, 14402−14412.

  3. Lijuan Gui, Jun Yan, Junyuan Zhao, Shiya Wang, Yingying Ji, Ji Liu, Jinsheng Wu, Kang Yuan, Heng Liu,* Dawei Deng* and Zhenwei Yuan*, Hypochlorite activatable ratiometric fluorescent probe based on endoplasmic reticulum stress for imaging of atherosclerosis, Biosensors and Bioelectronics, 2023, 240, 115660.

  4. Ruixi Li, Jingxuan Guo, Yishan Duan, Xian Liud, Lijuan Guib, Yue Xu, Xiangkai Kong, Yongjun Li, Haiyan Chen,* Zhenwei Yuan*, Monitoring inflammation-cancer progression by cell viscosity, polarity and leucine aminopeptidase using multicolor fluorescent probe, Chemical Engineering Journal, 2022, 435, 135043.

  5. Yue Xu, Hua Li, Shufen Xu, Xian Liu, Jingjing Lin, Haiyan Chen,* and Zhenwei Yuan*, Light-Triggered Fluorescence Self-Reporting Nitric Oxide Release from Coumarin Analogues for Accelerating Wound Healing and Synergistic Antimicrobial Applications, Journal of Medicinal Chemistry, 2022, 65, 424−435.


袁振伟
副教授
院系：必赢766net手机版生物医学工程与诊断药学系
招生方向：制药工程学、生物医学工程、生物与医药
实验室：实训楼504西
电子邮箱：yuanzhenwei@cpu.edu.
办公室：实训楼408
个人简介

袁振伟，博士，副教授，研究生导师，先后入选江苏省“科技副总”计划、安徽省“科技副总”计划、“博士后创新人才支持计划”，获厦门市科技进步奖三等奖（3/3），并担任江苏省生物医学工程学会生物医学光子学分会青年委员、《中国药科大学学报》青年编委。围绕肿瘤等重大疾病精准诊疗与放射治疗中的的临床问题，先后主持国家重点研发计划课题、国家自然科学基金、江苏省产学研合作项目、中央高校科研业务费重点项目、拉萨市重点科技计划项目、中国药科大学-南京中硼联康医疗科技有限公司联合实验室项目、中国药科大学-安徽中莱实业有限公司健康金寨联合实验室项目等，并以第一作者或者通讯作者在核化学、药物化学、以及化学生物学等领域权威期刊等刊物发表SCI论文30余篇，申请专利8项；并积极与医院、企业开展产学研合作。近年来，指导学生先后获得中国国际大学生创新大赛国赛金奖、全国大学生生命科学竞赛国赛特等奖、全国生物医学工程创新设计竞赛国赛一等奖、江苏省生物医学工程创新竞赛特等奖等奖项。

研究方向

  1. 基于硼中子俘获治疗（BNCT）的靶向硼药的设计合成及其成药性研究

  2. 基于疾病诊疗导向的光学/超声学分子开发


承担项目情况

  1. 国家重点研发计划子课题（2023YFE0197700）；

  2. 国家自然科学基金青年基金（82001891）；

  3. 中央高校基本科研业务费重点项目（2632022ZD01）；

  4. 江苏省产学研合作项目（BY20230124）；

  5. 拉萨市重点科技计划项目（LSKJ202419）；

  6. 中国药科大学-南京中硼联康医疗科技有限公司BNCT靶向硼药开发联合实验室项目（校合2024-工002）；

  7. 中国药科大学-安徽中莱实业有限公司健康金寨联合实验室项目（校合2024-工021）；

  8. 博士后创新人才支持计划（BX20190389）


代表性科研成果

  1. Jingxuan Guo, Jia Sun, Donghui Liu, Ji Liu, Lijuan Gui, Man Luo, Dexin Kong, Sainaiwaiergul Wusiman, Chang Yang, Ting Liu,* Zhenwei Yuan*, and Ruixi Li*, Developing a Two-Photon “AND” Logic Probe and Its Application in Alzheimer’s Disease Differentiation, Analytical Chemistry, 2023, 95, 16868−16876.

  2. Jun Yan, Kaizhen Wang, Lijuan Gui, Xian Liu, Yingying Ji, Jingjing Lin, Man Luo, Hong Xu, Jingxuan Lv, Fang Tan,* Liangting Lin,* and Zhenwei Yuan*, Diagnosing Orthotopic Lung Tumor Using a NTR-Activatable Near Infrared Fluorescent Probe by Tracheal Inhalation, Analytical Chemistry, 2023, 95, 14402−14412.

  3. Lijuan Gui, Jun Yan, Junyuan Zhao, Shiya Wang, Yingying Ji, Ji Liu, Jinsheng Wu, Kang Yuan, Heng Liu,* Dawei Deng* and Zhenwei Yuan*, Hypochlorite activatable ratiometric fluorescent probe based on endoplasmic reticulum stress for imaging of atherosclerosis, Biosensors and Bioelectronics, 2023, 240, 115660.

  4. Ruixi Li, Jingxuan Guo, Yishan Duan, Xian Liud, Lijuan Guib, Yue Xu, Xiangkai Kong, Yongjun Li, Haiyan Chen,* Zhenwei Yuan*, Monitoring inflammation-cancer progression by cell viscosity, polarity and leucine aminopeptidase using multicolor fluorescent probe, Chemical Engineering Journal, 2022, 435, 135043.

  5. Yue Xu, Hua Li, Shufen Xu, Xian Liu, Jingjing Lin, Haiyan Chen,* and Zhenwei Yuan*, Light-Triggered Fluorescence Self-Reporting Nitric Oxide Release from Coumarin Analogues for Accelerating Wound Healing and Synergistic Antimicrobial Applications, Journal of Medicinal Chemistry, 2022, 65, 424−435.